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Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryos

09/16/2016

Scientists at the Hubrecht Institute have shown that both the local organization of the genome and the sensitivity of genetic switches, ensure that Hox-genes are activated in the embryo. The research is published today, ahead of print, on the website of Genes & Development.

Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryos
Roel Neijts, Shilu Amin, Carina van Rooijen, Sander Tan, Menno P. Creyghton, Wouter de Laat, and Jacqueline Deschamps

The original Press Release can be found here.

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