` CSHLPress.com - endosome signaling plant

CSHL Press News

Endosome-Mediated Signaling in Plants

07/01/2007
Endosome-Mediated Signaling in Plants


In a paper that will be published online in advance of its July 1st publication date, Drs. Niko Geldner, Joanne Chory and colleagues (The Salk Institute and HHMI) demonstrate that endosomes can function as signaling platforms in plants, as well as in animals.

"These findings will influence our thinking of the evolutionary origins of endosomes and hopefully help us to understand why cells use them as signaling compartments," noted lead author of the paper, Dr. Niko Geldner.

Endosomes were once thought to function solely in the inactivation of receptors and the down-regulation of cell signaling. Work in animal cells over the past several years has shown that receptor endocytosis can actually facilitate signaling through the cell, by bringing signaling components in contact with their activated receptors.

Drs. Geldner, Chory and collaborators now extend the range of endosome-mediated signaling into the plant kingdom. The researchers show that the growth-promoting brassinosteroid receptor (BRI1) is trafficked through endosomes to enhance activation of this growth response pathway, which affects both shoot and root growth.

Dr. Chory is hopeful that these results “will serve as a springboard for future studies aimed at unraveling the mechanics of how plants grow."


Genes & Development is a publication of the Cold Spring Harbor Laboratory Press. The Cold Spring Harbor Laboratory is a private, non-profit, basic research and educational institution. Scientists at the Laboratory conduct groundbreaking research in cancer, neurobiology, plant molecular genetics, genomics and bioinformatics. The Laboratory is recognized internationally for its educational activities, which include an extensive program of scientific meetings and courses that attract more than 8000 scientists to the campus each year. For more information about the Cold Spring Harbor Laboratory, visit http://www.cshl.org or call the Department of Public Affairs at (516) 367-8455.

Contact:
Heather Cosel-Pieper
Genes & Development
Cold Spring Harbor Laboratory
tel. (516) 422-4018
fax (516) 422-4093




Return to CSHL Press News index