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New book on intermediary metabolism reveals intriguing complexity

05/11/2011

COLD SPRING HARBOR, N.Y. (May 11, 2011) “Metabolism is Not Boring!” asserts the introduction to a recent special issue of Science (Vol 330, 3 December 2010). On the contrary, the ways in which cells obtain energy, use external nutrients, and assemble the building blocks of macromolecules are crucial for life. And the basics of these processes—intermediary metabolism—are similar from the single-celled to multicellular organisms. This gives special importance to a new book by Harvard University's Dan Fraenkel on what studies of baker’s yeast, Saccharomyces cerevisiae, have taught us about intermediary metabolism.

Its topics include central metabolic pathways; catabolism; fermentation; respiration; the biosynthesis of small molecules, including cofactors and lipids; transport and compartments; storage molecules; aspects of inorganic ion metabolism; stress; issues of metabolic toxicity; and the global analysis of metabolism. In featured sections, the book also addresses the history of the field, describing the thinking that led to key experiments; and identifies areas where our knowledge remains thin.

Yeast Intermediary Metabolism meets a serious need: it provides a straightforward yet comprehensive treatment of ordinary metabolism suitable for students throughout their training in biology. The book is essential reading for yeast specialists but all investigators of eukaryote biology will find it an indispensable source of knowledge, distilled from Dan Fraenkel's many years of teaching and research.

About the book:
Yeast Intermediary Metabolism was written by Dan G. Fraenkel (Department of Microbiology and Molecular Genetics at Harvard Medical School in Boston) and published by Cold Spring Harbor Laboratory Press (©2011). It is available in hardcover (978-0-879697-97-6), is 434 pages in length and has a trim size of 6 x 9 inches. For more information, see http://www.cshlpress.com/link/yeastintermet.htm.

About the author:
Dr. Dan G. Fraenkel obtained his Ph.D. at Harvard Medical School, then became a Professor in the Department of Microbiology and Molecular Genetics, and has remained there ever since. Now Professor Emeritus, his present title is Senior Lecturer in Microbiology and Molecular Genetics. His special research interest is in microbial glycolysis, and his current work is focused on the control of flux in yeast glycolysis.

About Cold Spring Harbor Laboratory Press:
Cold Spring Harbor Laboratory Press is an internationally renowned publisher of books, journals, and electronic media, located on Long Island, New York. Since 1933, the Press has furthered the advance and spread of scientific knowledge in all areas of genetics and molecular biology, including cancer biology, plant science, bioinformatics, and neurobiology. The Press is a division of Cold Spring Harbor Laboratory, an innovator in life science research and the education of scientists, students, and the public. For more information, visit www.cshlpress.com.

Contact:
Elizabeth Powers, Book Marketing and Sales Account Manager
powerse@cshl.edu ; 516-422-4101



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