The Biology of Lipids: Trafficking, Regulation, and Function|
COLD SPRING HARBOR, N.Y. (July 20, 2011)
As the major structural component of cell membranes, lipids not only serve as barriers but also play active roles in cellular function. The fission and fusion of lipid membranes underlies the majority of protein trafficking in cells. Lipids are also critical in signal transduction; the interconversion of membrane-localized and soluble species is central to numerous signaling pathways that connect cell-surface receptors with intracellular effectors.
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive review of lipid biology. The contributors explore the synthesis, metabolism, and distribution of lipid species in the cell; the composition of lipid rafts and their roles in protein trafficking and signaling; and the biophysical behavior of lipids and membranes. They also discuss models and techniques to study lipid dynamics and to characterize cellular lipidomes.
Including discussions of diseases in which lipids play a role and the functions of lipids in virus replication, this volume is an indispensable reference for biochemists, cell and molecular biologists, and biophysicists interested in lipid biology.
About the book:
The Biology of Lipids: Trafficking, Regulation, and Function was edited by Kai Simons (Max Planck Institute of Molecular Cell Biology and Genetics) and published by Cold Spring Harbor Laboratory Press (© 2011). It is available in hardcover (978-1-936113-39-2), is 334 pages in length, with 45 color and 33 black and white illustrations. For more information, see www.cshlpress.com/link/biolipids.htm
About Cold Spring Harbor Laboratory Press:
Cold Spring Harbor Laboratory Press is an internationally renowned publisher of books, journals, and electronic media, located on Long Island, New York. Since 1933, the Press has furthered the advance and spread of scientific knowledge in all areas of genetics and molecular biology, including cancer biology, plant science, bioinformatics, and neurobiology. The Press is a division of Cold Spring Harbor Laboratory, an innovator in life science research and the education of scientists, students, and the public. For more information, visit www.cshlpress.com.
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